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This course provides a succinct overview of the emerging discipline of materials informatics at the intersection of materials science, computational science, and information science. You will discover specific opportunities afforded by this new field in accelerating materials development and deployment efforts. The course places particular emphasis on materials exhibiting hierarchical internal structures spanning multiple length and structure scales and the impediments involved in establishing invertible process-structure-property (PSP) linkages for these materials. You will discuss modern data sciences and innovative cyber-infrastructure tools, which are likely to play a critical and pivotal role in addressing the above challenges.